{"id":340018,"date":"2017-05-04T06:28:16","date_gmt":"2017-05-03T22:28:16","guid":{"rendered":"http:\/\/techcrunch.com\/?p=1485193"},"modified":"2017-05-04T06:28:16","modified_gmt":"2017-05-03T22:28:16","slug":"scientists-have-eliminated-hiv-in-mice-using-crispr","status":"publish","type":"post","link":"https:\/\/people.utm.my\/asmawisham\/scientists-have-eliminated-hiv-in-mice-using-crispr\/","title":{"rendered":"Scientists have eliminated HIV in mice using CRISPR"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=738\" class=\"\"\/><\/p>\n<p id=\"speakable-summary\">An important breakthrough has been made in the eradication of\u00a0AIDs.\u00a0Scientists have found they can successfully\u00a0snip out the HIV virus from mouse cells using CRISPR\/Cas9 technology.<\/p>\n<p>Right now patients with the deadly virus must use a toxic concoction of anti-retroviral medications to suppress the virus from replicating. However, CRISPR\/Cas9 can be programmed to chop out any genetic code in the body with scissor-like precision, including, possibly, all HIV-1 DNA within the body. And if you cut out the DNA, you stop the virus from being able to make copies of itself.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1485216\" src=\"https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/https-2f2fblueprint-api-production-s3-amazonaws-com2fuploads2fcard2fimage2f4658762f445ef1f2-ff7a-4427-9012-f23bd978da9d.jpg?w=372&amp;h=265\" alt=\"\" width=\"372\" height=\"265\" srcset=\"https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/https-2f2fblueprint-api-production-s3-amazonaws-com2fuploads2fcard2fimage2f4658762f445ef1f2-ff7a-4427-9012-f23bd978da9d.jpg 372w, https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/https-2f2fblueprint-api-production-s3-amazonaws-com2fuploads2fcard2fimage2f4658762f445ef1f2-ff7a-4427-9012-f23bd978da9d.jpg?w=150&amp;h=107 150w, https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/https-2f2fblueprint-api-production-s3-amazonaws-com2fuploads2fcard2fimage2f4658762f445ef1f2-ff7a-4427-9012-f23bd978da9d.jpg?w=300&amp;h=214 300w\" sizes=\"(max-width: 372px) 100vw, 372px\"\/>First published in the journal <a target=\"_blank\" href=\"http:\/\/sci-hub.io\/10.1016\/j.ymthe.2017.03.012\" rel=\"noopener noreferrer\">Molecular Therapy<\/a>, the team is the first to show HIV can be completely annihilated from the body using CRISPR. And with impressive effect. After just one treatment, scientists were able to show the technique had successfully removed all traces of the infection within mouse organs and tissue.<\/p>\n<p>However, it\u2019s not a permanent solution and it\u2019s still early days for the crew \u2014 the study merely builds on a previous proof-of-concept study they conducted last year and the technique has only been used on mice so far. But, should the scientists be able to replicate their findings, the technique could move to human trials in the future.<\/p>\n<p>\u201cThe next stage would be to repeat the study in primates, a more suitable animal model where HIV infection induces disease, in order to further demonstrate elimination of HIV-1 DNA in latently infected T cells and other sanctuary sites for HIV-1, including brain cells,\u201d said co-author of the study Dr. Khalili in a statement. \u201cOur eventual goal is a clinical trial in human patients.\u201d<\/p>\n<p><small>Featured Image: <a target=\"_blank\" href=\"https:\/\/www.flickr.com\/photos\/nickharris1\/7287033916\/in\/photolist-c6VXiN-bk9j7m-bk9jg7-7PxvWU-SkpCwT-dYzLBw-hQmbHT-2vC7E-9g3Jww-aMTbZZ-mEqcTr-6wuHGb-6wuHCw-6wqxxe-3KA7N9-87wmry-hM6Ey-DbVY7M-H1Zsqr-8ZpTpg-aUgTFZ-81AYir-ooSas-3MSJvo-8VXf8P-6uioMw-4gPo3w-5Haf77-6KVdG1-6QsB1L-roCLSj-4gUvTT-4yoNPV-4hbwnh-6yT8Rw-aUgTtr-9CfDyy-gGktfN-7E9MMy-2GdUe-7t64g2-cs3R8U-4MvNjr-5dcWum-d5HMof-anZ5ZT-ci9o8Y-n6zog-6JRCwG-2fqBLZ\">Nick Harris<\/a>\/<a target=\"_blank\" href=\"https:\/\/www.flickr.com\/\">Flickr<\/a> UNDER A <a target=\"_blank\" href=\"http:\/\/creativecommons.org\/licenses\/by\/2.0\/\">CC BY 2.0<\/a> LICENSE<\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" width=\"680\" height=\"452\" src=\"https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=680\" class=\"attachment-large size-large wp-post-image\" alt=\"\" srcset=\"https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=680 680w, https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=1360 1360w, https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=150 150w, https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=300 300w, https:\/\/tctechcrunch2011.files.wordpress.com\/2017\/05\/7287033916_ed0b523713_o.jpg?w=768 768w\" sizes=\"(max-width: 680px) 100vw, 680px\" \/>&nbsp;An important breakthrough has been made in the eradication of AIDs. Scientists have found they can successfully snip out the HIV virus from mouse cells using CRISPR\/Cas9 technology. <a href=\"https:\/\/techcrunch.com\/2017\/05\/03\/scientists-have-eliminated-hiv-in-mice-using-crispr\/?ncid=rss\">Read More<\/a><\/p>\n<div class=\"feedflare\">\n<a href=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?a=keqf-t7NG5c:k5_tUCjMssc:2mJPEYqXBVI\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?d=2mJPEYqXBVI\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?a=keqf-t7NG5c:k5_tUCjMssc:7Q72WNTAKBA\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?d=7Q72WNTAKBA\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?a=keqf-t7NG5c:k5_tUCjMssc:yIl2AUoC8zA\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?d=yIl2AUoC8zA\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?a=keqf-t7NG5c:k5_tUCjMssc:-BTjWOF_DHI\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?i=keqf-t7NG5c:k5_tUCjMssc:-BTjWOF_DHI\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?a=keqf-t7NG5c:k5_tUCjMssc:D7DqB2pKExk\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?i=keqf-t7NG5c:k5_tUCjMssc:D7DqB2pKExk\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?a=keqf-t7NG5c:k5_tUCjMssc:qj6IDK7rITs\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/Techcrunch?d=qj6IDK7rITs\" border=\"0\"><\/img><\/a>\n<\/div>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/Techcrunch\/~4\/keqf-t7NG5c\" height=\"1\" width=\"1\" alt=\"\"\/> <\/p>\n","protected":false},"author":5817,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[25],"tags":[59,66,26],"class_list":["post-340018","post","type-post","status-publish","format-standard","hentry","category-technology","tag-media","tag-techcrunch","tag-technology"],"_links":{"self":[{"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/posts\/340018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/users\/5817"}],"replies":[{"embeddable":true,"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/comments?post=340018"}],"version-history":[{"count":0,"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/posts\/340018\/revisions"}],"wp:attachment":[{"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/media?parent=340018"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/categories?post=340018"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/people.utm.my\/asmawisham\/wp-json\/wp\/v2\/tags?post=340018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}