{"id":1182,"date":"2020-09-01T09:18:42","date_gmt":"2020-09-01T09:18:42","guid":{"rendered":"https:\/\/people.utm.my\/chualeesuan\/?page_id=1182"},"modified":"2020-09-01T13:54:43","modified_gmt":"2020-09-01T13:54:43","slug":"botany-and-herbal-chemistry","status":"publish","type":"page","link":"https:\/\/people.utm.my\/chualeesuan\/botany-and-herbal-chemistry\/","title":{"rendered":"MKKT 1013: Botany and Herbal Chemistry"},"content":{"rendered":"<p style=\"text-align: center\"><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/DIBR7742.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1227 aligncenter\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/DIBR7742-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/DIBR7742-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/DIBR7742-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/DIBR7742.jpg 1024w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><span style=\"color: #339966\"><em>Green, refreshing, &amp; healthy &#8230;&#8230;<\/em><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff\"><strong>Botany<\/strong>:<\/span> Botany is the science of plant life involving plant biology. A botanist, plant scientist or phytologist who specialises in this field.<\/p>\n<p><span style=\"color: #993366\">&amp;<\/span><\/p>\n<p><strong><span style=\"color: #0000ff\">Herbal Chemistry<\/span>: <\/strong>Chemistry about the herbal plants, focusing on phytochemistry (plant derived chemical compounds) of herbs.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff\">Botany and herbal chemistry<\/span> is an interesting subject to further explore the essence of herbal plants in this tropical rain forest.<\/p>\n<p><!--more--><\/p>\n<p><span style=\"color: #0000ff\">Why study plants ?<\/span><\/p>\n<ol>\n<li>Provide oxygen we breath.<\/li>\n<li>Provide ozone layer as UV screen<\/li>\n<li>Provide a diversity of foods (the only producer)<\/li>\n<li>Provide fiber (wood, paper, food)<\/li>\n<li>Provide fossil fuel.<\/li>\n<li>Provide medicine<\/li>\n<li>Provide latex, resin<\/li>\n<li>Provide essential oils<\/li>\n<li>Provide decoration<\/li>\n<li>Provide job.<\/li>\n<li>Provide many more&#8230;&#8230;&#8230;&#8230;&#8230;..<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><!--nextpage--><\/p>\n<p><strong>Top 10 herbs in Malaysia<\/strong><\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/top-10-herbs.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1197 aligncenter\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/top-10-herbs-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/top-10-herbs-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/top-10-herbs-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/top-10-herbs.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p style=\"text-align: center\">The King of the herbs: <em>Eurycoma longifolia<\/em><\/p>\n<p style=\"text-align: center\">The Queen of the herbs: <em>Labisia pumila<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/WHO-data.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1202 aligncenter\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/WHO-data-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/WHO-data-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/WHO-data-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/WHO-data.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Many local people are still consuming the decoction of the herbs for health promotion and overall well-being till to date. From the chemistry point of view, the herbs contain several beneficial and therapuetic phytochemicals which could be further developed into valuable products.<\/p>\n<p><!--nextpage--><\/p>\n<p style=\"text-align: center\"><strong>What is phytochemicals?<\/strong><\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/phytochemicals.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1204 aligncenter\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/phytochemicals-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/phytochemicals-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/phytochemicals-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/phytochemicals.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Phytochemicals can be classified into 5 major groups of compounds. Each herb has its own unique chemical composition of those compounds. Therefore, scientists and researchers would like to profile the phytochemicals in order to have better understanding about the herbs. The current research challenge is to discover the marker compound of each herb to prevent the problem of adulteration.<\/p>\n<p><!--nextpage--><\/p>\n<p>One of the most abundant groups of phytochemicals: <span style=\"color: #0000ff\"><strong>ALKALOIDS<\/strong><\/span><\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1207\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-function.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1209\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-function-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-function-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-function-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/alkaloids-function.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Many applications of alkaloids have been explored and developed from plants. Extraction and isolation methods, as well as analytical technique to confirm the presence of alkaloids are discussed in the class.<\/p>\n<p><!--nextpage--><\/p>\n<p style=\"text-align: center\">Potential application of phytochemicals: Rosmarinic acid from Orthosiphon aristatus (misai kucing)<\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-RA.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1239 aligncenter\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-RA-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-RA-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-RA-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-RA.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<h6>YL Ngo and <strong>LS Chua<\/strong><em>*, Anti-diabetic activity of rosmarinic acid rich fractions from Orthosiphon stamineus, <\/em><strong>Current Enzyme Inhibition<\/strong>, 14(2), 97-103, 2018.<\/h6>\n<p>&nbsp;<\/p>\n<p><!--nextpage--><\/p>\n<p style=\"text-align: center\"><strong>Flow of herbal extraction<\/strong><\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/flow-of-extraction.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1216 alignleft\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/flow-of-extraction-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/flow-of-extraction-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/flow-of-extraction-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/flow-of-extraction.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1234\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-1024x768.jpg 1024w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-1536x1152.jpg 1536w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/IMG_0872-2048x1536.jpg 2048w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Conventional extraction: maceration, decoction, Soxhlet, reflux, steam distillation and etc..<\/p>\n<p>Modern extraction: microwave &amp; ultrasound assisted technique, supercritical fluid extraction&#8230;..<\/p>\n<p>&nbsp;<\/p>\n<p>What are the differences of the above mentioned extraction techniques?<\/p>\n<p>Factor for consideration: type and stability of phytochemicals, complexity of downstream process &#8230;&#8230;.<\/p>\n<p>&nbsp;<\/p>\n<p><!--nextpage--><\/p>\n<p style=\"text-align: center\"><strong>Analytical techniques<\/strong><\/p>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-chrom.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1213\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-chrom-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-chrom-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-chrom-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-chrom.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-spectro.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1214\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-spectro-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-spectro-300x225.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-spectro-768x576.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/anal-tech-spectro.jpg 960w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>The principle of each analytical technique will be explained and discussed in the class. They are useful techniques to characterise and further understand your herbal extract and\/or herbal products. They have been used for quality control and standardization to ensure quality consistency &amp; safety of products.<\/p>\n<p>&nbsp;<\/p>\n<p><!--nextpage--><\/p>\n<h3 style=\"text-align: center\"><strong>Data analysis and interpretation<\/strong><\/h3>\n<h4>Huge datasets would be generated and difficult to analyze manually.<\/h4>\n<h4>Multivariate data analysis approach is recommended for data clustering &amp; pattern recognition.<\/h4>\n<p><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/Multivariate-data.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1221\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/Multivariate-data-300x169.jpg\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/Multivariate-data-300x169.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/Multivariate-data-1024x576.jpg 1024w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/Multivariate-data-768x432.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/Multivariate-data.jpg 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><a href=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1224\" src=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-300x169.jpg\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-300x169.jpg 300w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-1024x576.jpg 1024w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract-768x432.jpg 768w, https:\/\/people.utm.my\/chualeesuan\/wp-content\/uploads\/sites\/991\/2020\/09\/graphical-abstract.jpg 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>M.A.F. Azlah, <strong>L.S. Chua<\/strong>*, F.I. Abdullah, Y.F. Yam, A fast and reliable 2D-IR spectroscopic technique for herbal leaves classification. <strong>Vibrational Spectroscopy<\/strong>, 106, 103014, 2020.<\/p>\n<p><strong>LS Chua<\/strong>*, CH Lau, NIM Ismail, CY Chew, <em>Phytochemical profile of Orthosiphon aristatus extracts after storage: rosmarinic acid and other caffeic acid derivatives<\/em>. <strong>Phytomedicine<\/strong>. 39, 49-55, 2018.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Green, refreshing, &amp; healthy &#8230;&#8230; &nbsp; Botany: Botany is the science of plant life involving plant biology. A botanist, plant scientist or phytologist who specialises in this field. &amp; Herbal Chemistry: Chemistry about the herbal plants, focusing on phytochemistry (plant derived chemical compounds) of herbs. &nbsp; Botany and herbal chemistry is an interesting subject to [&hellip;]<\/p>\n","protected":false},"author":13566,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1182","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/pages\/1182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/users\/13566"}],"replies":[{"embeddable":true,"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/comments?post=1182"}],"version-history":[{"count":43,"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/pages\/1182\/revisions"}],"predecessor-version":[{"id":1243,"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/pages\/1182\/revisions\/1243"}],"wp:attachment":[{"href":"https:\/\/people.utm.my\/chualeesuan\/wp-json\/wp\/v2\/media?parent=1182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}