My Research
https://utmscholar.utm.my/Scholar/ScholarInfoDetails/yyYr
Animal Cell Technology, Stem Cell Culture, Microcarrier Technology, Fermentation Technology, Bioprocess Development
Current Project
EXPANSION OF 3-DIMENSIONAL (3D) CULTURE OF HUMAN MESENCHYMAL STEM CELL ON THE NOVEL CELLULOSE BASED TYPE MICROCARRIERS
Mesenchymal stem cell (MSC) capacity to self-renew and differentiate into specialized cell have provided great promises in the regenerative medicine technology. The proposed project is to develop a suitable three-dimensional (3D) culture for expansion of stem cells using commercial microcarrier and novel cellulose based microcarriers from oil palm empty fruit bunch (OPEFB). Culturing parameters with the most suitable microcarrier identified in this study will be used to culture the expansion of MSC and used to explore the potential of microcarrier derived from the Oil Palm Empty Fruit Bunch (OPEFB). This proposed project will help to understand the expansion of stem cells in 3D novel cellulose based microcarrier made from OPEFB which could provide cost-effective microcarrier for high cell viability, strong adhesion, and efficient attachment for large scale expansion.
ACTIVE GRANTS
UTM Fundamental Research (UTMFr) (Principal Investigator)
EXPANSION OF 3-DIMENSIONAL (3D) CULTURE OF HUMAN MESENCHYMAL STEM CELL ON THE NOVEL CELLULOSE BASED TYPE MICROCARRIER
Fundamental Research Grant (Collaborator/Member)
Effects of oxygen transfer coefficient on intracellular product yield and cell growth in scaling-up of fermentation process from miniature to pilot scale bioreactor
UTM GUP Tier 2 (Collaborator/Member)
Characterisations of the physiology of mammalian cell lines in small scale culture
COMPLETED GRANTS
UTM GUP Tier 1
SCREENING OF MICROCARRIERS FOR MAMMALIAN MESENCHYMAL STEM CELLS IN MICROWELL ATTACHMENT PLATE
Networking Grant with UMP
Expansion of Vero cells on low-cost ultraviolet/ozone (UVO) treated polystyrene (PS) microcarriers for Newcastle disease virus (NDV)production
UTM GUP Tier 2