Carbohydrate Polymers

Genipin-cross-linked kappa-carrageenan/carboxymethyl cellulose beads and effects on beta-carotene release

Beads of kappa-carrageenan/sodium carboxymethylcellulose were prepared based on different blend formulations using genipin, a natural and non-toxic cross-linking reagent. Different genipin concentrations were used to study the effects on swelling ratio of the beads in different pH values under simulated gastrointestinal tract condition. It was found the beads released beta-carotene slower and lesser after being cross-linked, exhibited enhanced network stability and structure to be applied as suitable hydrogel for drug carrier.

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Authors:

Ida Idayu Muhamad, Ng Hui Hui, Noor Anis Mustapha & Lim Shu Fen