Publications and Technical Reports

  • Elucidation of GDC-0941 binding to PI3Kα isoform via in vitro mutagenesis of non-conserved amino acids of PI3Kα (2016). Syazwani I. Amran,  Ian G. Jennings and Philip E. Thompson. Conference Proceedings (ICBME 2016)
  • Deep Learning Methods and Optimization Algorithms in Bioinformatics Field : A Review (2016). Nor Erne Nazira Bazin, Syazwani Itri Amran, Amirah Baharin. International Journal of Innovative Computing.
  • Potent inhibitors of PI3 kinase that have anti-proliferative activity only when delivered as prodrug forms (2013). N. J. O’Brien, S. I. Amran, J. Medan, B. Cleary, L. W. Deady, I. G. Jennings, P. E. Thompson, B. M. Abbott. ChemMedChem · (Tier level : Q1, IF : 3.06)
  • Definition of the binding mode of a new class of phosphoinositide 3-kinase alpha-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis (2012). Z. Zheng, S. I. Amran, J. Zhu, O. Schmidt-Kittler, K. W. Kinzler, B. Vogelstein, P. R. Shepherd, P. E. Thompson, I. G. Jennings.  Biochem J. (Tier level : Q1, IF : 3.74)
  • Isoform selective inhibition of Phosphoinositide 3-kinase : Identification of a new region of non-conserved amino acids critical for p110alpha inhibition (2011). Z. Zheng, S. I. Amran, P. E. Thompson, I. G. Jennings. Molecular Pharmacology (Tier Level : Q1, IF : 4.883)
  • Biochemical & Cellular Studies of PI3Kinase Inhibition (2015) – PhD Dissertation
  • Mutagenesis of specific non-conserved residues on PI3 Kinase for the discovery of isoform-selective PI3 Kinase inhibitors (2008) – Honours Degree Dissertation
  • ‘Melatah’ : From psychological, biological and cultural perspectives (2004) – Foundation Studies Research Project