Cleaning Validation
- Ensure an appropriate level of cleanliness of manufacturing equipment and facility.
- The validation of cleaning procedures is a clear requirement of cGMP.
- Besides assuring chemical cleanliness, the microbiological aspects of equipment cleaning should be considered.
- Prevent the accumulation of dirt and microbial contamination which would affect the product quality.
- Minimize the risk of cross contamination from the earlier activity to the subsequent activity (cross contamination)
CLEANING: The removal of soil particles from surfaces by mechanical, manual or chemical methods.
SANITIZING: Treatment of a cleaned surface with a chemical or physical agent to destroy disease/spoilage causing organisms. Reduces total vegetative cell population to a safe level.
DISINFECTING: Destruction of all vegetative state organisms.
STERILIZING: The complete destruction of all organisms, including spores.
Let's explore the importance of cleaning validation in the pharmaceutical industry...............
https://www.renderforest.com/watch-89318768?queue_id=101030682&quality=0
