Our first research book has now been published by UTM Publisher. The book has 12 chapters altogether, compiling research on proteins carried out by UTM researchers and their collaborators. It is now available for purchase at:
“Proteins are the basic building blocks of life. They are defined as large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a variety of functions in the cell, including catalysing metabolic and biochemical reactions, assisting DNA replication, responding to external and internal stimuli, and transporting molecules from one location to another intra-cellularly or extra-cellularly. The study of proteins is important in the fields of biomedicine, environmental sciences, and for industrial applications. The understanding on how protein works at the molecular level assists in the development of new disease therapy, discovery and improvement of the activity of industrially- important enzymes, and discovery of beneficial secondary metabolites in medicinal plants, among many other interesting applications.
Investigation of proteins at the molecular level requires specialised instruments and precise techniques. Other than the commonly used sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and Western blotting (also known as protein immunoblotting), there are many other advanced techniques currently used which include surface plasmon resonance (SPR) spectroscopy, mass spectrometry (MS), X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, cryo-electron microscopy (cryo-EM), and circular dichroism (CD) spectroscopy. Computational methods are also indispensable in supporting wet lab experiments, and to provide precious information not currently observable with wet lab experiments.
This edited book is aimed at showcasing various research on proteins previously or currently being carried out at UTM and at affiliated laboratories. With the acquisition of increasingly sophisticated instruments, software, and the development of many new techniques, research on protein science is currently on the rise. This book demonstrates the research capability of our young and established researchers, and hopefully will serve as a networking guide for researchers interested in the field.”